いいえ、どっちもありません。
having regrets about ~ を使う時は、時間に関係ないもの、例えば、I have regrets about my relationships, などの時に使います。
しかし、もし ~ が時間に関係ある時、例えば、"life," which is actually not just life but "lifetime," you use "in" to specify duration instead of using about.
In latin, in + --- is often used as a time or place word, and ab/de (which means about in latin) is used for objects.
You should try googling your question with the world "life" and see which one comes up. English is derived from Latin, so a lot of the grammar rules are similar.
あ、ありがとうございますm(._.)m
おおー勉強になるー
？？
ええと…？
では、( )内には何を入れたら良いのでしょう…
我が生涯に一片の悔いなし という表現です